General (brain) health and performance
Storoschuk K, Wood TR, Stubbs BJ. A systematic review and meta-regression of exogenous ketone infusion rates and resulting ketosis – a tool for clinicians and researchers. Frontiers in Physiology. 2023 Jun 28;14:1202186. doi: 10.3389/fphys.2023.1202186.
Storoschuk K, Gharios RT, Galpin AJ, House BT, Wood TR. Strength and multiple types of physical activity, but not low muscle mass, independently predict cognitive function in NHANES 1999-2002. Lifestyle Medicine. 2023;e90. https://doi.org/10.1002/lim2.90
Nicola L, Loo SJQ, Lyon G, Turknett J, Wood TR. Does resistance training in older adults lead to structural brain changes associated with a lower risk of Alzheimer’s dementia? A narrative review. Ageing Research Reviews. 2024 May 30:102356. doi: 10.1016/j.arr.2024.102356.
Conti F, McCue JJ, DiTuro P, Galpin AJ, Wood TR. Mitigating Traumatic Brain Injury: A Narrative Review of Supplementation and Dietary Protocols. Nutrients. 2024 Jul 26;16(15):2430. doi: 10.3390/nu16152430. PMID: 39125311; PMCID: PMC11314487.
Potter GDM, Tinsley GM, Wood TR, Garner D, Galpin AJ., Dreamy Dwellings: How the Sleep Environment Affects Sleep Health in Adults — A Narrative Review. Lifestyle Medicine 6,4 (2025): 6, e70022.
Turknett J, Wood TR. Demand Coupling Drives Neurodegeneration: A Model of Age-Related Cognitive Decline and Dementia. Cells. 2022; 11(18):2789. doi: 10.3390/cells11182789. PMID: 36139364
Heath R, Wood TR. Why have the benefits of DHA not been borne out in the treatment and prevention of Alzheimer’s Disease: a narrative review focused on DHA metabolism and adipose tissue. Int J Mol Sci. 2021 Oct 31;22(21):11826. doi: 10.3390/ijms222111826. PMID: 34769257
Scholl J, Mailing L, Wood TR. Reframing nutritional microbiota studies to reflect an inherent metabolic flexibility of the human gut. mBIO 2021 Apr 13;12(2):e00579-21. doi: 10.1128/mBio.00579-21. PMID: 33849977
Potter GDM, Wood T. The Future of Shift Work: Circadian Biology Meets Personalised Medicine and Behavioural Science. Front Nutr. 2020; 7: 116. doi: 10.3389/fnut.2020.00116. PMID: 32850937
Wood T, Nance EA. Disease-directed engineering for physiology-driven treatment interventions. APL Bioengineering. 2019 Dec; 3(4): 040901. doi: 10.1063/1.5117299. PMID: 31673672
Cucuzzella MT, Tondt J, Dockter NE, Saslow L, Wood TR. A low-carbohydrate survey: Evidence for sustainable metabolic syndrome reversal. J Insulin Res. 2017;2(1). doi: 10.4102/jir.v2i1.30
Wood T, Kelly C. Insulin, glucose and beta-hydroxybutyrate responses to a medium-chain triglyceride-based sports supplement: A pilot study. J Insulin Res. 2017;2(1). doi: 10.4102/jir.v2i1.20
Kuhnle GG, Joosen AM, Wood TR, Runswick SA, Griffin JL, Bingham SA. Detection and quantification of sucrose as dietary biomarker using gas chromatography and liquid chromatography with mass spectrometry. Rapid Commun Mass Spectrom. 2008;22(3):279-82. doi: 10.1002/rcm.3355. PMID: 18181249.
Preterm birth – clinical studies
Kolnik SE, Jones K, Upadhyay K, Wood TR, Juul SE, Valentine GC. Increased Adherence to a Neonatal Care Bundle Reduced the Rate of Severe Intraventricular Hemorrhage in Preterm Neonates. Pediatrics. 2023 Sep 1;152(3):e2021056104. doi: 10.1542/peds.2021-056104. PMID: 37609772.
Kolnik SE, Marquard R, Brandon O, Puia-Dumitrescu M, Valentine GC, Law JB, Natarajan N, Dighe M, Mourad PD, Wood TR, Mietzsch U. Preterm Infants Variability in Cerebral Near-Infrared Spectroscopy Measurements in the First 72-hours After Birth. Pediatric Research. 2023 Oct;94(4):1408-1415. doi: 10.1038/s41390-023-02618-x
Strobel KM, Wood TR, Valentine GC, German K, Gogcu S, Hendrixson DT, Kolnik SE, Law JB, Mayock DE, Comstock BA, Heagerty PJ, Juul SE. Contemporary Definitions of Infant Growth Failure and Neurodevelopmental and Behavioral Outcomes in Extremely Premature Infants at Two Years of Age. J Perinatology. 2024 Jan 9. doi: 10.1038/s41372-023-01852-9. Epub ahead of print. PMID: 38195921.
Valentine GC, Perez KM, Wood TR, Mayock DE, Law JB, Kolnik S, Strobel KM, Brandon OC, Comstock BA, Heagerty PJ, Juul SE. Time to regain birthweight and association with neurodevelopmental outcomes among extremely preterm newborns. J Perinatol. 2024 Apr;44(4):554-560. doi: 10.1038/s41372-024-01869-8. Epub 2024 Jan 9. PMID: 38195922.
Wood TR, Davenport P, Heagerty PJ, Sola-Visner M, Juul SE, Patel RM. Association of Platelet Transfusion with Death or Neurodevelopmental Impairment in Children born Extremely Preterm. JAMA Network Open. 2024 Jan 2;7(1):e2352394. doi: 10.1001/jamanetworkopen.2023.52394. PMID: 38261320; PMCID: PMC10807258.
Valentine GC, Perez KM, Wood TR, Mayock DE, Law JB, Kolnik SE, Strobel KM, Brandon OC, Comstock BA, Heagerty PJ, Juul SE. Time to Regain Birthweight and Association with Neurodevelopmental Outcomes among Extremely Preterm Newborns. J Perinatology. 2024 Jan 9. doi: 10.1038/s41372-024-01869-8. Epub ahead of print. PMID: 38195922.
Kolnik SE, Sahota A, Wood TR, German K, Puia-Dumitrescu M, Mietzsch U, Dighe M, Law JB. Cranial Point-of-Care Ultrasound for Neonatal Providers: A Feasibility Study. J Ultrasound Med. 2024 Jun;43(6):1089-1097. doi: 10.1002/jum.16437. Epub 2024 Feb 25. PMID: 38404126.
Strobel KM, Wood TR, Valentine GC, Brandon OC, Hendrixson DT, Mayock DE, Perez KM, Puia-Dumitrescu M, Heagerty PJ, Juul SE. Effect of early antibiotic exposure on necrotizing enterocolitis and growth in extremely preterm infants. Pediatr Res. 2025 Feb 15. doi: 10.1038/s41390-025-03928-y. Epub ahead of print. PMID: 39955429.
German K, Wood TR, Gogcu S, Heagerty PJ, Mayock DE, Comstock BA, Puia-Dumitrescu M, Kolnik S, Mietzsch U, Law J, Perez K, Valentine G, Bammler TK, Juul SE; PENUT Trial Consortium. Neurodevelopmental outcomes after red cell transfusion exposure in male versus female extremely preterm infants. Pediatric Research. 2025 Jun 2. doi: 10.1038/s41390-025-04149-z. Epub ahead of print. PMID: 40456918.
Valentine GC, Rue T, Brandon OC, Perez KM, Wood TR, Rent S, Barbut G, Abadi M, Workneh R, Metaferia G, et al. Evaluation of First-Week Fluid Intake and Maximal Weight Loss Percentage with In-Hospital Adverse Outcomes Among Moderately and Very Preterm Newborns in Ethiopia. Children. 2025; 12(7):872.
Patel K, Wood TR, Horner D, Puia-Dumitrescu M, German K, Strobel KM, Perez K, Valentine GC, Law JB, Comstock B, et al. Childhood Differences in Healthcare Utilization Between Extremely Preterm Infants and the General Population. Children. 2025; 12(8):979.
German K, Wood TR, Gogcu S, Heagerty PJ, Mayock DE, Comstock BA, Puia-Dumitrescu M, Kolnik S, Mietzsch U, Law J, Perez K, Valentine G, Bammler TK, Juul SE; PENUT Trial Consortium. Neurodevelopmental outcomes after red cell transfusion exposure in male versus female extremely preterm infants. Pediatr Res. 2025 Jun 2. doi: 10.1038/s41390-025-04149-z. Epub ahead of print. PMID: 40456918.
Valentine GC, Brandon OC, Perez KM, Strobel KM, Mayock DE, Law JB, Neches S, German K, Kolnik SE, Heagerty PJ, Wood TR, Juul SE. The Association of Time to Regain Birthweight with In-Hospital Outcomes Among Extremely Preterm Newborns in the United States. Pediatric Research [In Press].
DiNucci KF, Rue TC, Brandon OC, Corry KA, Mayock DE, Heagerty PJ, Juul SE, Wood TR, Prenatal Magnesium Sulfate Exposure Is Not Associated with Different Neurodevelopmental Outcomes by Sex in Extremely Preterm Infants. Brain Sciences. 2025, 15, 1273.
Perez KM, Puia-Dumitrescu M, Comstock BA, Wood TR, Mayock DE, Heagerty PJ, Juul SE. Patterns of Infections Among Extremely Preterm Infants Enrolled in the Preterm Erythropoietin Neuroprotection (PENUT) Trial. Journal of Clinical Medicine. 2023 Apr 4;12(7):2703. doi: 10.3390/jcm12072703. PMID: 37048786
Brandon O, Perez KM, Kolnik SE, Juul SE, Wood TR, Valentine GC. Increasing Sodium Variability in the First 96-Hours after Birth is Associated with Adverse In-Hospital Outcomes of Preterm Newborns. Curr Dev Nutr. 2023 Jan; 7(1):e100026. doi: 10.1016/j.cdnut.2022.100026
Wood TR, Juul SE, German K, Law JB, Kolnik SE, Puia-Dumitrescu M, Mietzsch U, Gogcu S, Comstock BA, Li S, Mayock DE, Heagerty PJ. Predicting 2-year Neurodevelopmental Outcomes in Extremely Premature Infants Using Graphical Network and Machine Learning Approaches. eClinicalMedicine. 2023 Feb 1; 56:101782. doi: https://doi.org/10.1016/j.eclinm.2022.101782. PMID: 36618896
Kolnik SE, Jones K, Upadhyay K, Wood TR, Juul SE, Valentine GC. Increased Adherence to a Neonatal Care Bundle Reduced the Rate of Severe Intraventricular Hemorrhage in Preterm Neonates. Pediatrics. [In Press]
Puia-Dumitrescu M, Wood TR, Comstock BA, Law KB, German K, Perez KM, Gogcu S, Mayock DE, Heagerty PJ, Juul SE. Dexamethasone and (methyl)prednisolone use and 2-year neurodevelopmental outcomes in extremely preterm infants: Results from the PENUT Trial Cohort. JAMA Network Open. 2022 Mar 1;5(3):e221947. doi: 10.1001/jamanetworkopen.2022.1947. PMID: 35275165
Valentine GC, Perez KM, Wood TR, Mayock DE, Comstock BA, Puia-Dumitrescu M, Heagerty PJ, and Juul SE on behalf of the PENUT Trial consortium. Postnatal Maximal Weight Loss, Fluid Administration, and Outcomes in Extremely Preterm Newborns. J Perinatol. 2022 Aug;42(8):1008-1016. doi: 10.1038/s41372-022-01369-7. PMID: 35338252
Heath RJ, Klevebro S, Wood TR. Maternal and neonatal polyunsaturated fatty acid intake and risk of neurodevelopmental impairment in premature infants. Int J Mol Sci. 2022 Jan 9;23(2):700. doi: 10.3390/ijms23020700. PMID: 35054885
Juul SE, Wood TR, Comstock BA, Perez KM, Gogcu S, Puia-Dumitrescu M, Berkelhamer S, Heagerty PJ. Deaths in a modern cohort of extremely preterm infants: Analysis from the PENUT Trial. JAMA Network Open. 2022 Feb 1;5(2):e2146404. doi: 10.1001/jamanetworkopen.2021.46404. PMID: 35129596
Law JB, Comstock BA, Richards TL, Traudt CM, Wood TR, Mayock DE, Heagerty PJ, and Juul SE on behalf of the PENUT Trial consortium. Diffusion Tensor Imaging to Assess the Effect of Early Erythropoietin on Brain Development Among Extremely Preterm Infants in the Preterm Erythropoietin Neuroprotection (PENUT) Trial. Brain Sci. 2021 Oct 16;11(10):1360. doi: 10.3390/brainsci11101360. PMID: 34679424
Wood TR, Parikh PK, Comstock BA, Law JB, Bammler TK, Mayock DE, Heagerty PJ, Burbacher T, and Juul SE on behalf of the PENUT Trial consortium. Early Biomarkers of Hypoxia and Inflammation and Two-Year Neurodevelopmental Outcomes in the Preterm Erythropoietin Neuroprotection (PENUT) Trial. eBioMedicine. 2021 Oct;72:103605. doi: 10.1016/j.ebiom.2021.103605. PMID: 34619638
Law JB, Wood TR, Gogcu S, Comstock BA, Dighe M, Perez K, Puia-Dumitrescu M, Shaw DW, Wright J, Widness JA, Mayock DE, Heagerty PJ, and Juul SE on behalf of the PENUT Trial consortium. Intracranial Hemorrhage and 2-year Neurodevelopmental Outcomes in Extremely Preterm Infants. J Pediatr. 2021 Nov;238:124-134.e10. doi: 10.1016/j.jpeds.2021.06.071. PMID: 34217769
Puia-Dumitrescu M, Comstock BA, Li S, Heagerty PJ, Perez K, Law JB, Wood TR, Gogcu S, Mayock DE, and Juul SE on behalf of the PENUT Trial consortium. The use of opioids and benzodiazepines and 2-year neurodevelopmental outcomes in extremely low gestational age infants. JAMA Network Open. 2021 Jul 1;4(7):e2115998. doi: 10.1001/jamanetworkopen.2021.15998. PMID: 34232302
Klevebro S, Juul SE, Wood T. A More Comprehensive Approach to the Neuroprotective Potential of Long-Chain Polyunsaturated Fatty Acids in Preterm Infants Is Needed—Should We Consider Maternal Diet and the n-6:n-3 Fatty Acid Ratio? Front Pediatr. 2019; 7: 533. doi: 10.3389/fped.2019.00533. PMID: 31998669
Birth asphyxia and hypoxic-ischaemic encephalopathy – clinical studies
Mietzsch U, Wood TR, Wu TW, Natarajan N, Glass HC, Gonzalez FF, Mayock DE, Comstock BA, Heagerty PJ, Juul SE, Wu YW; HEAL Study Group. Early Glycemic State and Outcomes of Neonates With Hypoxic-Ischemic Encephalopathy. Pediatrics. 2023 Oct 1;152(4):e2022060965. doi: 10.1542/peds.2022-060965.
Tetarbe M, Wisnowski JL, Geyer E, Tamrazi B, Wood TR, Mietzsch U, Blüml S, Wu T-W. Cerebral glucose concentration in neonatal encephalopathy during therapeutic hypothermia. J Pediatr. 2023 Oct;261:113560. doi: 10.1016/j.jpeds.2023.113560.
Rao R, Comstock BA, Wu TW, Mietzsch U, Mayock DE, Gonzalez FF, Wood TR, Heagerty PJ, Juul SE, Wu YW. Time to Reaching Target Cooling Temperature and 2-year Outcomes in Infants with Hypoxic-Ischemic Encephalopathy. J Pediatr. 2024 Mar;266:113853. doi: 10.1016/j.jpeds.2023.113853. Epub 2023 Nov 23. PMID: 38006967; PMCID: PMC11509115.
Mietzsch U, Kolnik SE, Wood TR, Natarajan N, Gonzalez FF, Glass H, Mayock DE, Bonifacio SL, Van Meurs K, Comstock BA, Heagerty PJ, Wu TW, Wu YW, Juul SE; HEAL Trial Study Group. Evolution of the Sarnat exam and association with 2-year outcomes in infants with moderate or severe hypoxic-ischaemic encephalopathy: a secondary analysis of the HEAL Trial. Arch Dis Child Fetal Neonatal Ed. 2024 Apr 18;109(3):308-316. doi: 10.1136/archdischild-2023-326102. PMID: 38071538; PMCID: PMC11031347.
Wu TW, Schmicker R, Wood TR, Mietzsch U, Comstock B, Heagerty PJ, Rao R, Gonzalez F, Juul S, Wu YW. Esophageal versus Rectal Temperature Monitoring during Whole-body Therapeutic Hypothermia for Hypoxic-ischemic Encephalopathy: Association with Short and Long-term Outcomes. J Pediatr. 2024 Feb 1:113933. doi: 10.1016/j.jpeds.2024.113933. PMID: 38309524.
Glass H, Wood TR, Comstock BA, Numis A, Bonifacio S, Cornet MC, Gonzalez FF, Kolnik SE, Li Y, Mathur A, Mietzech U, Wu TW, Wusthoff CJ, Heagerty PJ, Juul SE, Wu YW. Predictors of Death or Severe Impairment in Neonates With Hypoxic-Ischemic Encephalopathy. JAMA Network Open. 2024;7(12):e2449188. doi: 10.1001/jamanetworkopen.2024.49188
Lenahan A, Mietzsch U, Wood TR, Press Callahan K, Weiss EM, Miller DE, German K, Natarajan N, Puia-Dumitrescu M, Esposito V, Kolnik S, Law JB. Characteristics, Genetic Testing, and Diagnoses of Infants with Neonatal Encephalopathy Not Due Hypoxic Ischemic Encephalopathy - A Cohort Study. J Pediatr. 2023 Jun 1:113533. 10.1016/j.jpeds.2023.113533. PMID: 37269901.
Mietzsch U, Wood TR, Wu T-W, Juul SE, Niranjana Natarajan N, Hannah C. Glass HC, Gonzalez FF, Mayock DE, Comstock BA, Heagerty PJ, Wu YW. Glycemic profile during the first 12 hours of life in neonates with HIE is associated with outcome. Pediatrics [In Press].
Mietzsch U, Law JB, Puia-Dumitrescu M, Juul SE, Wood TR. Temperature dysregulation during therapeutic hypothermia predicts long-term outcome in neonates with HIE. J Cereb Blood Flow Metab 2023 Mar 8;271678X231162174. doi: 10.1177/0271678X231162174. PMID: 36883364
Natarajan N, Benedetti G, Perez F, Wood TR, German K, Lockrow J, Puia-Dumitrescu M, Myers E, Mietzsch U. Association between early EEG background and outcomes in infants with mild HIE undergoing therapeutic hypothermia. Pediatr Neurol. 2022 Sep;134:52-58. doi: 10.1016/j.pediatrneurol.2022.06.006. PMID: 35835026
Mietzsch U, Radhakrishnan R, Boyle FA, Juul S, Wood TR. Temperature profile during therapeutic hypothermia as a physiologic biomarker of outcome in neonates with moderate to severe hypoxic-ischemic encephalopathy (HIE). J Physiol. 2020 Jan;598(2):415-424. doi: 10.1113/JP278790. PMID: 31777079
Other neuroscience and neonatology articles
Juul SE, Wood TR. Pipeline to Neonatal Clinical Transformation: The Importance of Preclinical Data. Clin Perinatol. 2024 Sep;51(3):735-748. doi: 10.1016/j.clp.2024.04.011. Epub 2024 May 16. PMID: 39095107.
Horner D, Jepsen JRM, Chawes B, Vinding R, Rosenberg JB, Mohammadzadeh P, Luo Y, Fagerlund B, Flensborg-Madsen T, Wood TR, Felix JF, Monnerup L, Glenthøj BY, Bønnelykke K, Ebdrup BH, Stokholm J, Rasmussen MA. Maternal dietary patterns, breastfeeding duration, and their association with child cognitive function and head circumference growth: A prospective mother-child cohort study. PLoS Med. 2025 Apr 10;22(4):e1004454. doi: 10.1371/journal.pmed.1004454. PMID: 40208849; PMCID: PMC11984734.
Martinez-King C, Rose C, Perez KM, Brandon O, Sahota A, Nallaseth K, Yang TJ, Tibayan S, Kulkarni S, Hameed A, Gray KJ, Wood TR, Valentine GC. The association between oral risk assessment and obstetric and newborn outcomes. Pregnancy. 2025, 1: e70114.
Kukka AJ, Berkelhamer SK, Eilevstjønn J, Wood TR, Basnet O, Ashish KC. Observational study comparing heart rate in crying and non-crying but breathing infants at birth. BMJ Paediatrics Open. 2023 Apr;7(1):e001886. doi: 10.1136/bmjpo-2023-001886. PMID: 37028906
Ashish KC, Kong SYJ, Haaland SH, Eilevstjønn J, Myklebust H, Bastola RC, Wood TR, Niermeyer S, Berkelhamer S. Increased risk of bradycardia in vigorous infants receiving early as compared to delayed cord clamping at birth. J Perinatol. 2022 Dec 31. doi: 10.1038/s41372-022-01593-1. PMID: 36587054
Kolnik SE, Wood TR. Role of Vitamin E in Neonatal Neuroprotection: A Comprehensive Narrative Review. Life. 2022 Jul 20;12(7):1083. doi: 10.3390/life12071083. PMID: 35888171
Liao R, Wood TR, Nance EA. Nanotherapeutic modulation of excitotoxicity and oxidative stress in acute brain injury. Nanobiomedicine. 2020 Nov 4;7. doi: 10.1177/1849543520970819. PMID: 35186151
Wood T, Stubbs BJ, Juul SE. Exogenous ketone bodies as promising neuroprotective agents for developmental brain injury. Dev Neurosci. 2019 May 14;:1-12. doi: 10.1159/000499563. PMID: 31085911
Curtis C, Zhang M, Liao R, Wood T, Nance E. Systems-level thinking for nanoparticle-mediated therapeutic delivery to neurological diseases. WIREs Nanomedicine and Nanobiotechnology. 2017 Mar;9(2). doi: 10.1002/wnan.1422. PMID: 27562224
Wood T, Thoresen M. Physiological Responses to Hypothermia. Seminars in Fetal and Neonatal Medicine. 2015 Apr;20(2):87-96. doi: 10.1016/j.siny.2014.10.005. PMID: 25457082
Neonatal neuroscience – basic science
White OR, Corry KA, Moralejo DH, Law JB, Snyder JM, Mietzsch U, Juul SE, Wood TR. Rectal temperature after hypoxia-ischemia predicts white matter and cortical pathology in the near-term ferret. Pediatric Research. 2023 Sep 8. doi: 10.1038/s41390-023-02793-x.
Schimek N, Wood TR, Beck DAC, McKenna M, Toghani A, Nance E. High-fidelity predictions of diffusion in the brain microenvironment. Biophys J. 2024 Nov 19;123(22):3935-3950. doi: 10.1016/j.bpj.2024.10.005. Epub 2024 Oct 10. PMID: 39390745; PMCID: PMC11617630.
Jin ZR, Corry KA, Brandon OC, Magoon MJ, Helmbrecht H, Moralejo DH, Bassett R, Kolbik SE, Boyle PM, Juul SE, Nance EA, Wood TR. Multi-modal screening for synergistic neuroprotection of extremely preterm brain injury. Bioengineering & Translational Medicine 2025;e70058.
Brandon OC, White OR, Corry KA, Stanescu A, Ariaye A, Moralejo DH, Law JB, Kolnik SE, Juul SE, Wood TR. Ferreting Out the Effects of Neonatal Hypoxia–Ischemia and Sex on Ferret Cortical Gyrification. Life. 2025; 15(9):1428.
Gundersen JK, Sabir H, Wood TR, Osredkar D, Falck M, Løberg EM, Walløe L, Menassa DA, Thoresen M. Restraint stress during neonatal hypoxia-ischemia alters brain injury following normothermia and hypothermia. Physiol Rep. 2023 Jan;11(1):e15562. doi: 10.14814/phy2.15562. PMID: 36636750
Kolnik SE, Corry KA, Hildahl K, Filteau J, White OR, Brandon O, Farid L, Shearlock AE, Moralejo DH, Juul SE, Nance EA, Wood TR. Vitamin E Decreases Cytotoxicity and Mitigates Inflammatory and Oxidative Stress Responses in a Ferret Organotypic Brain Slice Model of Neonatal Hypoxia-Ischemia. Dev Neurosci. 2022;44(4-5):233-245. doi: 10.1159/000522485. PMID: 35134797
Gundersen JK, Menassa DA, Wood TR, Walløe L, Thoresen M. The deleterious effect of crossfostering in rat pups on hypoxic-ischemic injury tolerance and hypothermic neuroprotection. Dev Neurosci. 2022;44(4-5):205-213. doi: 10.1159/000521438. PMID: 34915481
Wood TR, Hildahl K, Helmbrecht H, Corry KA, Moralejo DH, Kolnik SE, Prater KE, Juul SE, Nance EA. A ferret brain slice model of oxygen-glucose deprivation captures regional responses to perinatal injury and treatment associated with specific microglial phenotypes. Bioeng Transl Med. 2021 Nov 23;7(2):e10265. doi: 10.1002/btm2.10265. PMID: 35600642
Corry KA, White OR, Shearlock AE, Moralejo DH, Law JB, Snyder JM, Juul SE, Wood TR. Evaluating Neuroprotective Effects of Uridine, Erythropoietin, and Therapeutic Hypothermia in a Ferret Model of Inflammation-Sensitized Hypoxic-Ischemic Encephalopathy. Int J Mol Sci. 2021 Sep 11;22(18):9841. doi: 10.3390/ijms22189841. PMID: 34576001
Joseph A, Nyambura C, Bondurant D, Corry K, Beebout D, Wood TR, Pfaendtner WJ, Nance EA. Formulation and efficacy of catalase-loaded nanoparticles for the treatment of neonatal hypoxic-ischemic encephalopathy. Pharmaceutics. 2021 Jul 23;13(8):1131. doi: 10.3390/pharmaceutics13081131. PMID: 34452092
Wood TR, Vu PT, Comstock BA, Law JB, Mayock DE, Heagerty PJ, Burbacher T, Bammler TK, Juul SE. Cytokine and chemokine responses to injury and treatment in a nonhuman primate model of hypoxic-ischemic encephalopathy treated with hypothermia and erythropoietin. J Cereb Blood Flow Metab. 2021 Aug;41(8):2054-2066. doi: 10.1177/0271678X21991439. PMID: 33554708
Wood TR, Gundersen JK, Falck M, Maes E, Osredkar D, Løberg EM, Sabir H, Walløe L, Thoresen M. Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic-ischaemic brain injury: a single laboratory meta-analysis. Sci Rep. 2020 Jul 2;10(1):10833. doi: 10.1038/s41598-020-67532-2. PMID: 32616806
Liao R, Wood TR, Nance EA. Superoxide dismutase reduces monosodium glutamate-induced injury in an organotypic whole hemisphere brain slice model of excitotoxicity. J Biol Engineering. 2020;Feb 14:3. doi: 10.1186/s13036-020-0226-8
Wood T, Moralejo D, Corry K, Fisher C, Snyder J, Acuna V, Holden-Hunt A, Virk S, White O, Parikh P, Juul SE. A Ferret Model of Inflammation-Sensitized Late Preterm Hypoxic-Ischemic Brain Injury. JoVE. 2019; (153), e60131. doi: 10.3791/60131. PMID: 31814608.
Wood T, Moralejo D, Corry K, Snyder JM, Traudt C, Curtis C, Nance E, Parikh P, Juul SE. A Ferret Model of Encephalopathy of Prematurity. Dev Neurosci. 2019 May 10;:1-15. doi: 10.1159/000498968. PMID: 31079096
Wood TR, Snyder J, Corry K, Moralejo D, Parikh P, Juul SE. Ontogeny of white matter, toll-like receptor expression, and motor skills in the neonatal ferret. Int J Dev Neurosci. 2018 Nov;70:25-33. doi: 10.1016/j.ijdevneu.2018.05.006. PMID: 29791868
Falck M, Osredkar D, Maes E, Flatebø T, Wood TR, Walløe L, Sabir H, Thoresen M. Hypothermia Is Neuroprotective after Severe Hypoxic-Ischaemic Brain Injury in Neonatal Rats Pre-Exposed to PAM3CSK4. Dev Neurosci. 2018;40(3):189-197. doi: 10.1159/000487798. PMID: 29860252
Joseph A, Wood T, Chen E, Corry K, Snyder J, Juul S, Parikh P, Nance E. Curcumin-Loaded Polymeric Nanoparticles for Neuroprotection in Neonatal Rats with Hypoxic-Ischemic Encephalopathy. Nano Research 2018; 11, 5670–5688. doi: 10.1007/s12274-018-2104-y
Falck M, Osredkar D, Wood TR, Maes E, Flatebø T, Sabir H, Thoresen M. Neonatal Systemic Inflammation Induces Inflammatory Reactions and Brain Apoptosis in a Pathogen-Specific Manner. Neonatology. 2018;113(3):212-220. doi: 10.1159/000481980. PMID: 29275405
Wood T, Hobbs C, Falck M, Brun AC, Løberg EM, Thoresen M. Rectal temperature in the first five hours after hypoxia-ischaemia critically affects neuropathological outcomes in neonatal rats. Pediatric Research. 2018 Feb;83(2):536-544. doi: 10.1038/pr.2017.51. PMID: 28288145
Falck M, Osredkar D, Maes E, Flatebø T, Wood TR, Sabir H, Thoresen M. Hypothermic Neuronal Rescue from Infection-Sensitised Hypoxic-Ischaemic Brain Injury Is Pathogen Dependent. Dev Neurosci. 2017;39(1-4):238-247. doi: 10.1159/000455838. PMID: 28407632
Wood T, Osredkar D, Puchades M, Maes E, Falck M, Flatebø T, Walløe L, Sabir H, Thoresen M. Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia. Sci Rep. 2016 Mar 21;6:23430. doi: 10.1038/srep23430. PMID: 26997257
Wood T, Smit E, Maes E. Osredkar D, Falck M, Elstad M, Thoresen M. Monitoring of cerebral blood flow during hypoxia-ischaemia and resuscitation in the neonatal rat using laser speckle imaging. Physiol Rep. 2016 Apr;4(7). pii: e12749.
Sabir H, Wood T, Gill H, Dingley J, Liu X, Thoresen M. Xenon depresses aEEG background voltage activity whilst maintaining cardiovascular stability in sedated healthy newborn pigs. J Neuro Sci. 2016 Apr 15;363:140-4. doi: 10.1016/j.jns.2016.02.05. PMID: 27000239
Sabir H, Osredkar D, Maes E, Wood T, Thoresen M. Xenon combined with therapeutic hypothermia is not neuroprotective after severe hypoxia-ischemia in neonatal rats. PLoS One. 2016 Jun 2;11(6):e0156759. doi: 10.1371/journal.pone.0156759. PMID: 27253085
Smit E, Liu X, Jary S, Gill H, Wood T, Thoresen M. The effect of resuscitation in 100% oxygen on brain injury in a newborn rat model of severe hypoxic-ischaemic encephalopathy. Resuscitation. 2015 Nov;96:214-9. doi: 10.1016/j.resuscitation.2015.07.050. PMID: 26300234
Osredkar D, Sabir H, Falck M, Wood T, Maes E, Flatebø T, Puchades M, Thoresen M. Hypothermia does not reverse cellular responses caused by lipopolysaccharide in neonatal hypoxic-ischemic brain injury. Dev Neurosci. 2015;37(4-5):390-.7. doi: 10.1159/000430860. PMID: 26087775
Thoresen M, Hobbs CE, Wood T, Chakkarapani E, Dingley J. Cooling combined with immediate or delayed xenon inhalation provides equivalent long-term neuroprotection after neonatal hypoxia-ischemia. J Cereb Blood Flow Metab. 2009 Apr;29(4):707-14. doi: 10.1038/jcbfm.2008.163. PMID: 19142190.